Photodynamic Therapy Mediated by Fullerenes and Their Derivatives
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By Felipe F. Sperandio, Asheesh Gupta, Min Wang, Rakkiyappan Chandran, Magesh Sadasivam, Ying-Ying Huang, Long Y. Chiang & Michael R. Hamblin
This fifth volume in the monographs series was written and developed by an international team of experts from the U.S., Brazil, India, and China, including Harvard Medical School, the Harvard-MIT Division of Health Sciences and Technology, the University of Massachusetts, the University of Sao Paulo, Brazil, the Amity Institute of Nanotechnology, India, Guangxi Medical University, Nanning, China, as well as several other educational institutes and foundations.
Abstract: The fullerene molecule with its unique structure of 60 carbon atoms arranged in a soccer ball structure is a molecule of great potential for a variety of applications and has drawn the attention of many physicists, chemists and engineers. Recently, these nanostructures have also been studied for their biological activities with a view towards using them for biomedical applications. One of the possible therapies for which fullerenes may have a real medical application is the light based therapy called photodynamic therapy (PDT), which is a non-surgical, minimally invasive approach that has been used in the treatment of solid tumors and many non-malignant diseases.